The violence of Takfiri groups in recent years has involved countries all around the world. Non-Muslims and Muslims, both Shi'a and Sunnis, have been victims of the violence of Takfiri groups. By contrast, the Shiites response to the brutal acts of these groups has not exceeded the "legitimate defense" level and has not led to any retaliation, which Shiite scholars' intellectual beliefs seems to be one of the reasons behind it. Therefore, the kind of view of Imam Khomeini, as one of the most prominent Shiite scholars on the one hand and the provider of the political Islam differently than the other denominations, has stressed the importance  of the phenomenon of assassination and violence. The question of this article is that to what extent takfir and acts of violence against others are related to the political discourse of Imam Khomeini? According to the political and practical discourse of Imam Khomeini, it is believed that takhfir and violence are not the means to achieve the goals ... In this paper, the descriptive-analytic method was used which was carried out by a review of documents though the library research method. The most important finding of the article is that Imam, as one of the great scholars of Shiite history, rejects employing takfir, violence and assassination in the political life based on his philosophical foundations.